The `Five Sisters? was a row of five public houses and inns which were built opposite the Holyhead railway station, likely in the late 1860s. These were, from north to south, the Holland Arms Hotel, Dublin Packet, Sidney Inn, Globe Inn, and Blossoms Inn, the Sidney Inn having become part of the Dublin Packet in the twentieth century. The buildings in the middle of the row (the Dublin Packet, Globe, and formerly the Sidney Inn) are two storeys, while the end buildings (the Holland Arms and Blossoms Inn) are two-and-a-half stories. There are chimneys on the gables and where each building joins the next, and this spacing and division is preserved in the middle of the Dublin Packet.

The Holland Inn has two dormers in its roof with large window. The second story has two large vertical rectangular windows and the first story has a single door on the right and a larger, double-door entrance on the left. There is a small flat-roofed, single-storey extension to the north with a large service door. The north gable end lacks windows. The pub sign displays a white lion rampant on a blue shield, above which is another yellow lion. The background is a pattern of red, yellow and blue, resembling mantling.

The upper story of the Dublin Packet has four mullioned windows over a string course. The northern two windows are perceptibly lower than the southern two. The first story has two large mullioned windows, sunken into the wall and resting on red brickwork. To the north of each window is a single doorway. The pub sign displays a steamship sailing on a green sea.

The Globe, originally an inn, became first a dinner house and then a cafe. Its facade is similar in form to the Dublin Packet, with two vertical windows in the second storey over the cafe sign. The first storey is tiled and has a large window, to the north of which is a single door. It has two upper storey-windows similar in size and placement to the Holland Inn and Dublin packet, and its lower story similarly has a single door to the right and a large square window to the left. Indeed, it can probably be taken as exemplifying the basic `template? on which the other buildings in the row are based.

The Blossoms has timber-framed-styles facades to the east and south, both topped with gables. The eastern wall as a large sign in the gable and two second-storey vertical windows. The first storey has a single door to the right and a large triple door to the left. The eastern wall, however, is longer than the eastern faces of the other buildings, meaning that these doors and windows are oriented to the right of centre. The southern wall as a small sash window in the gable and a large rectangular sign in the second storey. In 2016, the Blossoms reopened as The Five Sisters.

(Sources: Hughes and Williams, Holyhead: The Story of a Port (Denbigh: 1967), p. 102; Daily Post, 27.07.2016; Welsh Newspapers Online: North Wales Chronicle, 17.10.1868)
A.N. Coward, RCAHMW, 01.05.2018